Endocrine Abstracts

Introduction: Type 1 diabetes is an endocrinopathy due to insulin deficiency. Its treatment consists in administering an exogenous insulin simulating the physiological secretion. The objective of this study was to evaluate glycemic variability in a group of adolescents with type 1 diabetes treated with human insulin.Method: This is a cross-sectional study, including type1 diabetic patients treated with human insulin, who underwent continuous glucose moni...

Introduction: During these last years, Intermittent fasting was emerging as an approach that improves weight and metabolic outcomes in obese subjects.Objective: To investigate the effects of 16:8 intermittent fasting on metabolic and inflammatory parameters in adult obese.Methods: This is a comparative interventional study conducted in 60 obese women consulting the obesity unit of the Institute of Nutrition of Tunis during the peri...

Introduction: Mauriac syndrome is typically characterised by poor glycaemic control in type 1 diabetics. It is associated with diabetes, hepatomegaly, disturbed liver function and severe staturo-weight delay.Observation: We report the case of a young type 1 diabetic patient referred to our department for further management of a glycaemic imbalance. The patient was 16 years old, type 1 diabetic for 10 years on insulin analogues, with a history of vitiligo...

Introduction: Obesity is recognized as a continuously growing, global public health problem. It is associated with increased risk of a variety of acute and chronic disorders.Objective: The aim of our work was to estimate the prevalence of obesity-related complications in a group of patients undergoing sleeve gastrectomy.Methodology: Retrospective, descriptive study of a group of obese candidates for bariatric surgery recruited from...

Objectives: The aim of our study was to assess the nutritional status of elderly diabetics.Methods: This was a descriptive cross-sectional study conducted at the National Institute of Nutrition in Tunis including 40 diabetics aged over 65 years. All patients underwent anthropometric measurements (weight, height, body mass index (BMI)), a biological assessment (fasting blood glucose, glycated haemoglobin (HbA1c)), a dietary survey and an assessment of nut...

Introduction: Glycemic variability (GV), defined as an integral component of glucose homeostasis, is emerging as an important metric to consider when assessing glycemic control in clinical practice. The aims of our study were to study glycemic variability among a group of adolescents with type 1 diabetes and to determine the factors influencing this parameter.Method: This is a cross-sectional analytical study, conducted at the National Institute of Nutri...

Introduction: Hyperuricemia is associated with an increased risk of cardiovascular diseases. The aim of this study was to examine the relationship between lipid profile and blood uric acid levels in an adult population with obesity.Methods: Retrospective study including 200 patients with obesity who consulted the Obesity Unit of the National Institute of Nutrition in Tunis in 2021. Data were collected from patients’ medical records. The lipid profil...

As type 2 diabetes mellitus (T2DM) is a metabolic disorder, it frequently poses challenges for patients in metabolizing uric acid, resulting in hyperuricemia (HUA). In this study, our objective is to investigate the risk factors of HUA among T2DM patients.Method: Patients with T2DM who were attended in the National Institute of Nutrition in Tunis, Tunisia, between August and November 2023 were included in this retrospective observational study. Diagnosin...

Introduction: Mean platelet volume (MPV) is an indicator of the average size and activity of platelets. Higher levels of MPV are encountered in conditions with increased production in response to increased destruction of platelets. Some studies suggest an association between impaired platelet function and vascular complications in patients with diabetes mellitus. The aim of our study is to prove this association.Methods: Descriptive cross-sectional study...

Introduction: Diabetes is known as a risk factor of microangiopathy which generally appear concomitantly. Diabetes is also the most common cause of peripheral polyneuropathy and all these complications are related to chronic hyperglycemia. The main objective of the present study is to determine the prevalence of the diabetic peripheral neuropathy (DPN) and its characteristics in people with normoalbuminuria.Methods: Descriptive cross-sectional study cond...